| Bioactivity | BChE-IN-20?is a?highly?potentBChE-selective inhibitor?and exhibits?IC50s of 105 and 2.3 nM?for?eqBChE and hBChE, respectively.?BChE-IN-20?inhibits?P glycoprotein with IC50?of 0.27 μM.?BChE-IN-20?is?a promising template to improve design and development of BChE-selective ligands of pharmaceutical interest, including inhibitors and fluorogenic probes. |
| Name | BChE-IN-20 |
| CAS | 1428439-79-5 |
| Formula | C27H39N5O2 |
| Molar Mass | 465.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Modesto de Candia, et al. In-vitro and in-silico studies of annelated 1,4,7,8-tetrahydroazocine ester derivatives as nanomolar selective inhibitors of human butyrylcholinesterase. Chem Biol Interact. 2023 Oct 13:386:110741. |
BChE-IN-20
CAS: 1428439-79-5 F: C27H39N5O2 W: 465.63
BChE-IN-20?is a?highly?potentBChE-selective inhibitor?and exhibits?IC50s of 105 and 2.3 nM?for?eqBChE and hBChE, respect
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