Bioactivity | BChE-IN-17 (compound 6n) is a potent and selective BChE inhibitor with IC50s of 10.5 nM and 32.5 nM for eqBChE and hBChE, respectively. BChE-IN-17 shows over 1000-fold selectivity to BChE against AChE. BChE-IN-17 shows low neurotoxicity and moderate neuroprotective effects[1]. |
Name | BChE-IN-17 |
CAS | 2425632-57-9 |
Formula | C23H23BrN2O4S2 |
Molar Mass | 535.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Tingkai Chen, et al. The structural modification and biological evaluation of tetrahydrothienopyridine derivatives as selective BChE inhibitors. Bioorg Med Chem Lett. 2023 Sep 1;93:129436. |