Bioactivity | BCTP is a TRPV1 antagonist. BCTP activated at low pH showed functional antagonist activity against human TRPV1 in CHO cells (IC50=18 nM). BCTP can be used in the study of chronic pain[1]. |
CAS | 464152-46-3 |
Formula | C17H16ClN3OS |
Molar Mass | 345.85 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Culshaw A J, et al. Identification and biological characterization of 6-aryl-7-isopropylquinazolinones as novel TRPV1 antagonists that are effective in models of chronic pain[J]. Journal of medicinal chemistry, 2006, 49(2): 471-474. |