Bioactivity | BCRP-IN-1 (compound 48) is a potent inhibitor of breast cancer resistance protein (BCRP), with IC50s of 2.92 μM and 2.46 μM in Hoechst 33342 assay and Pheophorbide A assay, respectively[1]. |
CAS | 765899-28-3 |
Formula | C16H14N4O4 |
Molar Mass | 326.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. "Kapil Juvale, et al. Investigation of quinazolines as inhibitors of breast cancer resistanceprotein (ABCG2). Bioorg Med Chem. 2013 Dec 15;21(24):7858-73. " |