| Bioactivity | BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR(498-514), biotinylated blocks BCL6-mediated transcriptional repression and kills lymphoma cells[1]. |
| Sequence | Ac-Arg-Ser-Glu-Ile-Ile-Ser-Thr-Ala-Pro-Ser-Ser-Trp-Val-Val-Pro-Gly-Pro-{Lys(biotin)} |
| Shortening | Ac-RSEIISTAPSSWVVPGP-{Lys(biotin)} |
| Formula | C98H155N25O29S |
| Molar Mass | 2179.49 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ghetu AF, et al. Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer. Mol Cell. 2008 Feb 15;29(3):384-91. |
BCOR(498-514), biotinylated
CAS: F: C98H155N25O29S W: 2179.49
BCOR(498-514), biotinylated is the minimal BCL6 binding domain with an KD value of 1.32 µM. BCOR(498-514), biotinylated
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