| Bioactivity | BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1]. | ||||||||||||
| Target | BCL6 | ||||||||||||
| Name | BCL6-IN-6 | ||||||||||||
| CAS | 2408882-54-0 | ||||||||||||
| Formula | C27H31FN6O2S | ||||||||||||
| Molar Mass | 522.64 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Guo W, et al. Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. J Med Chem. 2020;63(2):676-695. |
BCL6-IN-6
CAS: 2408882-54-0 F: C27H31FN6O2S W: 522.64
BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks th
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