BCL-xL/BCL-2 ligand 1_product_DataBase

CAS: 2941091-91-2 F: C48H53ClF3N5O7S3 W: 1000.61

BCL-xL/BCL-2 ligand 1 (compound 72-1) is a BCL-xL and BCL-2 protein ligand. BCL-xL/BCL-2 ligand 1 can be connected to th

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	BCL-xL/BCL-2 ligand 1 (compound 72-1) is a BCL-xL and BCL-2 protein ligand. BCL-xL/BCL-2 ligand 1 can be connected to the E3 ligase by a linker to form PROTACs (HY-161410)[1][2].
CAS	2941091-91-2
Formula	C48H53ClF3N5O7S3
Molar Mass	1000.61
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Guangrong Zheng, et al. Bcl-xl/bcl-2 dual degraders for treatment of cancers. WO2023107606A1. [2]. Nayak D, et al. Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun. 2024 Mar 29;15(1):2743.

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