| Bioactivity | BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, and inhibits the binding of K-, H-, and N-Ras to PI3Kα. BBO-10203 inhibits pAKT with an IC50 < 0.1 pM in BT474 cell[1]. |
| CAS | 2971769-60-3 |
| Formula | C34H30F2N6O3S |
| Molar Mass | 640.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xu R. et al., Compounds having a t-structure formed by at least four cycles for use in the treatment of cancer and other indications. WO2023154282. |
BBO-10203
CAS: 2971769-60-3 F: C34H30F2N6O3S W: 640.70
BBO-10203 (Compound 758) binds to the RBD region of PI3Kα, and inhibits the binding of K-, H-, and N-Ras to PI3Kα. BBO
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