| Bioactivity | BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials[1]. |
| Target | IC50: 160 nM(LpxC) |
| Invitro | BB-78485 可以抑制 LpxC，IC50 值为 160 nM[1]。BB-78485 对 D21 和 D22 (lpxC101) 有作用，MIC 值分别为 2 μg/mL 和 0.016 μg/mL[1]。BB-78485 对Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae和 Burkholderia cepacia的 MIC 值范围为 1μg/mL 至 32μg/mL[1]。 |
| Name | BB-78485 |
| CAS | 207732-11-4 |
| Formula | C23H20N2O4S |
| Molar Mass | 420.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Clements JM, et al. Antibacterial activities and characterization of novel inhibitors of LpxC. Antimicrob Agents Chemother. 2002;46(6):1793-1799. |
BB-78485
CAS: 207732-11-4 F: C23H20N2O4S W: 420.48
BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of
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