| Bioactivity | BB 0305179 (compound 59) is a potent anti-prion agent, with an IC50 of 4.7 μM. BB 0305179 inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain [1]. |
| Target | IC50: 4.7 ± 1.9 μM (PrPSc) |
| Name | BB 0305179 |
| CAS | 2512200-83-6 |
| Formula | C21H29NO |
| Molar Mass | 311.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Altieri A, et al. Generation, optimization and characterization of novel anti-prion compounds. Bioorg Med Chem. 2020 Nov 1;28(21):115717. |