Bioactivity | BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261)[1]. |
CAS | 233255-39-5 |
Formula | C22H25N3O4S |
Molar Mass | 427.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. McSharry JJ, et al., Susceptibilities of human cytomegalovirus clinical isolates to BAY38-4766, BAY43-9695, and ganciclovir. Antimicrob Agents Chemother. 2001 Oct;45(10):2925-7. |