Bioactivity | BAY-3153 is a selective CCR1 (C-C motif chemokine receptor 1) antagonist (human IC50=3 nM; rat IC50=11 nM; mice IC50=81 nM)[1]. |
In Vivo | BAY-3153 (10 mg/kg) treatment shows reduction of infiltrating macrophages in experimental renal ischemia/reperfusion model in mice[1]. |
Name | BAY-3153 |
CAS | 2771319-69-6 |
Formula | C25H29Cl2N3O4 |
Molar Mass | 506.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. https://www.sgc-ffm.uni-frankfurt.de/#!specificprobeoverview/BAY-3153 |