| Bioactivity | BAY 1892005 is a regulator of p53 protein and acts on p53 condensates without causing mutant p53 reactivation[1]. | ||||||||||||
| Invitro | BAY 1892005 在 p53 突变状态的细胞系 Huh7 (IC50=11.2 μM)、H358 (IC50=11.1 μM) 能抑制细胞增殖[1]。 0 --> BAY 1892005 相关抗体: | ||||||||||||
| Name | BAY 1892005 | ||||||||||||
| CAS | 2036352-13-1 | ||||||||||||
| Formula | C11H8ClFN2OS | ||||||||||||
| Molar Mass | 270.71 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Lemos C, et al. Identification of Small Molecules that Modulate Mutant p53 Condensation[J].iScience, 2020, 23(9):101517. |