| Bioactivity | BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM. BAY-155 leads to a strong expression down-regulation of the MEIS1 gene and up-regulation of CD11b and MNDA genes. BAY-155 shows anti-proliferative effects in AML/ALL (acute myeloid/lymphoblastic leukemia) models[1]. |
| Name | BAY-155 |
| CAS | 2163769-52-4 |
| Formula | C28H28F3N7OS |
| Molar Mass | 567.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brzezinka K, et al. Characterization of the Menin-MLL Interaction as Therapeutic Cancer Target. Cancers (Basel). 2020 Jan 14;12(1):201. |
BAY-155
CAS: 2163769-52-4 F: C28H28F3N7OS W: 567.63
BAY-155 is a potent and selective menin-MLL tool inhibitor, with an IC50 of 8 nM. BAY-155 leads to a strong expression d
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