| Bioactivity | BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner[1]. | ||||||
| Name | BAM(8-22) | ||||||
| CAS | 412961-36-5 | ||||||
| Shortening | VGRPEWWMDYQKRYG | ||||||
| Formula | C91H127N25O23S | ||||||
| Molar Mass | 1971.20 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Parul Sikand, et al. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. J Neurosci. 2011 May 18;31(20):7563-7. |
BAM(8-22)
CAS: 412961-36-5 F: C91H127N25O23S W: 1971.20
BAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled
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