Bioactivity | BACE1-IN-11 is a BACE1 inhibitor. BACE1-IN-11 has the BACE1 inhibitory activity with an IC50 value of 72 μM. BACE1-IN-11 can be used for the research of Alzheimer’s disease (AD) [1]. |
Invitro | BACE1-IN-11(compound 1) has the BACE1 inhibitory activity with an IC50 value of 72 μM[1]. |
Name | BACE1-IN-11 |
CAS | 1803952-77-3 |
Formula | C30H51N5O8S |
Molar Mass | 641.82 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Takuya Otani, et al. Macrocyclic BACE1 inhibitors with hydrophobic cross-linked structures: Optimization of ring size and ring structure. Bioorg Med Chem. 2021 Dec 15;52:116517. |