Bioactivity | B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group[1]. |
CAS | 103412-37-9 |
Sequence | Lys-Lys-Arg-{Hyp}-Pro-Gly-{Thi}-Ser-Phe-{Thi}-Arg |
Shortening | KKR-{Hyp}-PG-{Thi}-SF-{Thi}-R |
Formula | C62H95N19O14S2 |
Molar Mass | 1394.67 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |