| Bioactivity | Aβ-IN-3 (compound 1) is a potent amyloid β (Aβ) inhibitor. Aβ-IN-3 inhibits Aβ42 aggregation. However, Aβ-IN-3 can not alleviate the neurotoxicity of Aβ42 in SH-SY5Y cells. Aβ-IN-3 can not change the aggregation state of Aβ42 into a nontoxic one[1]. |
| Name | Aβ-IN-3 |
| CAS | 2477606-87-2 |
| Formula | C33H43N5O7 |
| Molar Mass | 621.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tanaka F, et al. Design and synthesis of β-strand-fixed peptides inhibiting aggregation of amyloid β-protein. Bioorg Med Chem. 2020 Sep 15;28(18):115676. |