| Bioactivity | Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and intracellular Ca2+ homeostasis failure caused by Halothane (HY-B1010)/Succinylcholine. Azumolene sodium (0.5-2.0 mg/kg) reduces [Ca2+]i (from 207 nM to 38 nM) in MH-susceptible skeletal muscle following intramuscular injection[1]. |
| CAS | 105336-14-9 |
| Formula | C13H9BrN4NaO3 |
| Molar Mass | 372.13 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Allen P D, Lopez J R, Sanchez V, et al. EU 4093 decreases intracellular [Ca2+] in skeletal muscle fibers from control and malignant hyperthermia-susceptible swine[J]. Anesthesiology, 1992, 76(1): 132-138. |
Azumolene sodium
CAS: 105336-14-9 F: C13H9BrN4NaO3 W: 372.13
Azumolene sodium (EU4093) is an analog of Dantrolene (HY-12542) that inhibits malignant hyperthermia (MH) syndrome and i
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