PeptideDB

Azithromycin hydrate

CAS: 117772-70-0 F: C38H76N2O14 W: 785.02

Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
Invitro Azithromycin (2 μM) augments rhinovirus-induced IFNβ expression in primary bronchial epithelial cells from asthmatics, which is associated with over-expression of RIG-I like receptors and repression of viral replication. Knockdown of MDA5, but not knockdown of RIG-I, diminishes azithromycin (2 μM)-enhanced viral-induced IFNβ expression in asthmatic primary bronchial epithelial cells[1]. Azithromycin specifically reduces MMP-9 mRNA and protein levels without affecting NF-κB in endotoxin-challenged monocytic THP-1 cells[2].
Name Azithromycin hydrate
CAS 117772-70-0
Formula C38H76N2O14
Molar Mass 785.02
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.