| Bioactivity | Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. | |||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. | |||||||||
| Name | Azido-PEG8-NHS ester | |||||||||
| CAS | 1204834-00-3 | |||||||||
| Formula | C23H40N4O12 | |||||||||
| Molar Mass | 564.58 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
|
Azido-PEG8-NHS ester
CAS: 1204834-00-3 F: C23H40N4O12 W: 564.58
Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azid
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.