| Bioactivity | Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2]. | ||||||||||||
| Invitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2]. | ||||||||||||
| Name | Azido-PEG6-amine | ||||||||||||
| CAS | 957486-82-7 | ||||||||||||
| Formula | C14H30N4O6 | ||||||||||||
| Molar Mass | 350.41 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Azido-PEG6-amine
CAS: 957486-82-7 F: C14H30N4O6 W: 350.41
Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a n
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