| Bioactivity | Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. | ||||||||||||
| Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. | ||||||||||||
| Name | Azido-PEG5-alcohol | ||||||||||||
| CAS | 86770-68-5 | ||||||||||||
| Formula | C10H21N3O5 | ||||||||||||
| Molar Mass | 263.29 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Azido-PEG5-alcohol
CAS: 86770-68-5 F: C10H21N3O5 W: 263.29
Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Az
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