| Bioactivity | Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis[1][3]. |
| Invitro | Azathioprine (0-50 μM, 48 hours) can induce severe intracellular GSH depletion with relevant concentrations in both primary rat and human hepatocytes[2]. Cell Viability Assay[2] Cell Line: |
| Name | Azathioprine |
| CAS | 446-86-6 |
| Formula | C9H7N7O2S |
| Molar Mass | 277.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |