| Bioactivity | Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV)[1]. |
| In Vivo | Azasetron could effectively penetrate through the skin and pass into the systemic circulation[2]. Animal Model: |
| Name | Azasetron hydrochloride |
| CAS | 123040-16-4 |
| Formula | C17H21Cl2N3O3 |
| Molar Mass | 386.27 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Sato, N., et al., Antagonistic activity of Y-25130 on 5-HT3 receptors. Jpn J Pharmacol, 1992. 59(4): p. 443-8. [2]. Haga, K., et al., The effects of orally administered Y-25130, a selective serotonin3-receptor antagonist, on chemotherapeutic agent-induced emesis. Jpn J Pharmacol, 1993. 63(3): p. 377-83. |
Azasetron hydrochloride
CAS: 123040-16-4 F: C17H21Cl2N3O3 W: 386.27
Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetro
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