| Bioactivity | Azaline (Azaline A) is a gonadotropin-releasing hormone (GnRH) receptor antagonist with a KD value of 0.48 nM. Azaline can effectively induce histamine release, with an effect comparable to that of GnRH, and it can completely inhibit ovulation at a dose of 2.0-3.0 μg per female rat. Azaline has potential applications in regulating reproductive functions[1]. |
| CAS | 134457-26-4 |
| Formula | C74H106ClN23O12 |
| Molar Mass | 1545.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rivier J, et al. Gonadotropin releasing hormone antagonists: novel structures incorporating N omega-cyano modified guanidine moieties. Biochem Biophys Res Commun. 1991 Apr 15;176(1):406-12. |
Azaline
CAS: 134457-26-4 F: C74H106ClN23O12 W: 1545.23
Azaline (Azaline A) is a gonadotropin-releasing hormone (GnRH) receptor antagonist with a KD value of 0.48 nM. Azaline c
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