Bioactivity | Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception[1]. |
Target | IC50: 1.37 nM (GnRH) |
CAS | 134457-28-6 |
Sequence | Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-Ser-{Phe<X>}-{d-Phe<X>}-Leu-{Lys<Ph>}-Pro-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino |
Shortening | Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-S-{Phe<X>}-{d-Phe<X>}-L-{Lys<Ph>}-P-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino |
Formula | C80H102ClN23O12 |
Molar Mass | 1613.27 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Samant MP, et al., Novel gonadotropin-releasing hormone antagonists with substitutions at position 5. Biopolymers. 2005;80(2-3):386-91. |