PeptideDB

Azaline B

CAS: 134457-28-6 F: C80H102ClN23O12 W: 1613.27

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in rese
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Bioactivity Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception[1].
Target IC50: 1.37 nM (GnRH)
CAS 134457-28-6
Sequence Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-Ser-{Phe<X>}-{d-Phe<X>}-Leu-{Lys<Ph>}-Pro-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino
Shortening Ac-{d-Ala<2Nal>}-{d-Phe<Cl>}-{d-Ala<Py>}-S-{Phe<X>}-{d-Phe<X>}-L-{Lys<Ph>}-P-{d-Ala} X=3-amino-1H-1,2,4-triazol-5-yl)amino
Formula C80H102ClN23O12
Molar Mass 1613.27
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Samant MP, et al., Novel gonadotropin-releasing hormone antagonists with substitutions at position 5. Biopolymers. 2005;80(2-3):386-91.