Bioactivity | Azalamellarin N is an inhibitor of pyroptosis and has different inhibitory effects on different pyroptosis inducers. Azalamellarin N inhibits pyroptosis by targeting molecules that act upstream of NLRP3 inflammasome activation, rather than directly targeting components of the NLRP3 inflammasome. Inhibitory potency against different pyroptosis inducers: Nigericin (HY-127019) > R837 (HY-B0180)[1]. |
Name | Azalamellarin N |
CAS | 1809535-57-6 |
Formula | C28H22N2O7 |
Molar Mass | 498.48 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Takouda J, et al. Identification of Azalamellarin N as a Pyroptosis Inhibitor. Biol Pharm Bull. 2024;47(1):28-36. |