| Bioactivity | Axl-IN-10 (Example 1) is a potent AXL inhibitor, with an IC50 of 5 nM. Axl-IN-10 has excellent transmembrane properties.Axl-IN-10 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-10 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1]. |
| Target | IC50: 5 nM (AXL) |
| Name | Axl-IN-10 |
| CAS | 2487649-61-4 |
| Formula | C27H25N7O2 |
| Molar Mass | 479.53 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1. |