PeptideDB

Aviptadil acetate

CAS: 1444827-29-5 F: C147H238N44O42S.C2H4O2 W: 3385.90

Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil aceta
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Aviptadil acetate is an analog vasoactive intestinal polypeptide (VIP) with potent vasodilatory effects. Aviptadil acetate induces pulmonary vasodilation and inhibits vascular SMCs proliferation, platelet aggregation. Aviptadil acetate can be used for the research of pulmonary fibrosis, pulmonary arterial hypertension (PAH) and SARS-CoV-2 caused respiratory failure, et al[1].
Invitro Aviptadil acetate (1 nM-10 μM) produces a concentration-dependent inhibition of CSE-induced cell death in L2 cells. At 10 μM, Aviptadil acetate reduces CSE-stimulated MMP activity and caspase-3 activation in L2 cells[1].
Name Aviptadil acetate
CAS 1444827-29-5
Shortening HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2
Formula C147H238N44O42S.C2H4O2
Molar Mass 3385.90
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)