| Bioactivity | Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. |
| Invitro | Avibactam is a molecule with little antibacterial activity, that inhibits class A and C β-lactamases, but not metallo types and Acinetobacter OXA carbapenemases[2]. Ceftazidime (HY-B0593)-Avibactam (0-256 mg/L) inhibits 16 blaKPC-2 positive and 1 of blaOXA-232 positive Klebsiella pneumonia growth with MIC50 and MIC90 for both 8 mg/L[4]. |
| Name | Avibactam sodium |
| CAS | 1192491-61-4 |
| Formula | C7H10N3NaO6S |
| Molar Mass | 287.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
Avibactam sodium
CAS: 1192491-61-4 F: C7H10N3NaO6S W: 287.23
Avibactam sodium (NXL-104)is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase
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