| Bioactivity | Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively[1]. | ||||||||||||
| Invitro | Avibactam is a molecule with little antibacterial activity, that inhibits class A and C β-lactamases, but not metallo types and Acinetobacter OXA carbapenemases[2]. Ceftazidime (HY-B0593)-Avibactam (0-256 mg/L) inhibits 16 blaKPC-2 positive and 1 of blaOXA-232 positive Klebsiella pneumonia growth with MIC50 and MIC90 for both 8 mg/L[4]. | ||||||||||||
| Name | Avibactam free acid | ||||||||||||
| CAS | 1192500-31-4 | ||||||||||||
| Formula | C7H11N3O6S | ||||||||||||
| Molar Mass | 265.24 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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Avibactam free acid
CAS: 1192500-31-4 F: C7H11N3O6S W: 265.24
Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactam
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