| Bioactivity | Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | ||||||
| Invitro | It is found that Autocamtide-2-related inhibitory peptide (TFA) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93, respectively, under the assay condition used[1]. | ||||||
| Name | Autocamtide-2-related inhibitory peptide TFA | ||||||
| Sequence | Lys-Lys-Ala-Lru-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu | ||||||
| Shortening | KKALRRQEAVDAL | ||||||
| Formula | C66H126N22O21F3 | ||||||
| Molar Mass | 1611.76 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |