Bioactivity | Auristatin F is a potent cytotoxin in antibo-conjugated drugs and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) [1][2]. | ||||||
Invitro | Auristatin F and Monomethyl Auristatin F (MMAF) are potent ADC cytotoxin used in antibody-drug conjugates[1]. | ||||||
Name | Auristatin F | ||||||
CAS | 163768-50-1 | ||||||
Formula | C40H67N5O8 | ||||||
Molar Mass | 745.99 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage |
*该产品在溶液状态不稳定,建议您现用现配,即刻使用。 |