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Aurantiamide acetate

CAS: 56121-42-7 F: C27H28N2O4 W: 444.52

Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsininhibitor isolated from Portulaca olerace
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Bioactivity Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of  inflammatory diseases[1][2].
Invitro Aurantiamide acetate inhibits cathepsin L (3.4.22.15) and cathepsin B (3.4.22.1) with IC50 of 12 μM and 49 μM, respectiveiy[1].
Name Aurantiamide acetate
CAS 56121-42-7
Formula C27H28N2O4
Molar Mass 444.52
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month