| Bioactivity | Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure[1]. |
| Name | Atriopeptin III (rat) |
| CAS | 90817-13-3 |
| Sequence | Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge:Cys3-Cys19) |
| Shortening | SSCFGGRIDRIGAQSGLGCNSFRY (Disulfide bridge:Cys3-Cys19) |
| Formula | C107H165N35O34S2 |
| Molar Mass | 2549.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Olsen UB, et al. Atriopeptin III improves renal functions in a ureter-obstructed rat kidney model. Eur J Pharmacol. 1986 Mar 18;122(2):191-6. [2]. Cole BR, et al. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. J Clin Invest. 1985 Dec;76(6):2413-5. |
Atriopeptin III (rat)
CAS: 90817-13-3 F: C107H165N35O34S2 W: 2549.80
Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic ag
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