Bioactivity | Atriopeptin II rat, mouse is an atrial natriuretic peptide, which acts as diuretic and natriuretic agent, and a potent relaxant of vascular smooth muscle[1]. |
Invitro | Atriopeptin II rat, mouse (10 nM, 100 min) 在大鼠离体胸主动脉中表现出血管舒张作用,增加环 GMP 浓度并激活环 GMP 激酶[1]。Atriopeptin II rat, mouse (0-100 nM) 可刺激睾酮生成,半最大刺激浓度为 2.6 nM[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Atriopeptin II (rat, mouse) 相关抗体: |
CAS | 89139-54-8 |
Sequence | Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg (Disulfide bridge: Cys3-Cys19) |
Shortening | SSCFGGRIDRIGAQSGLGCNSFR (Disulfide bridge: Cys3-Cys19) |
Formula | C98H156N34O32S2 |
Molar Mass | 2386.63 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Fiscus RR, et al., Atriopeptin II elevates cyclic GMP, activates cyclic GMP-dependent protein kinase and causes relaxation in rat thoracic aorta. Biochim Biophys Acta. 1985 Jul 30;846(1):179-84. [2]. Mukhopadhyay AK, et al., Testosterone production by mouse Leydig cells is stimulated in vitro by atrial natriuretic factor. FEBS Lett. 1986 Jun 23;202(1):111-6. |