| Bioactivity | Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589)[1]. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. |
| Invitro | Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation. |
| Name | Atorvastatin Epoxy Tetrahydrofuran Impurity |
| CAS | 873950-19-7 |
| Formula | C26H24FNO5 |
| Molar Mass | 449.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Klobčar S, et al. Isolation of oxidative degradation products of atorvastatin with supercritical fluidchromatography. Biomed Chromatogr. 2015 Dec;29(12):1901-6. |
Atorvastatin Epoxy Tetrahydrofuran Impurity
CAS: 873950-19-7 F: C26H24FNO5 W: 449.47
Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B
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