| Bioactivity | Atiprimod (Azaspirane) (dimaleate) is an anti-proliferative and anti-angiogenic agent that inhibits proliferation of all human cancer cell lines. Atiprimod (dimaleate) also induces Apoptosis and activates both caspase-9 and caspase-3 in T84 colon carcinoma cells. Atiprimod (dimaleate) inhibits both bFGF and VEGF induced proliferation and migration of human umbilical vein endothelial cells, resulting in disruption of cord formation. Atiprimod (dimaleate) reduces production of IL-6, VEGF and inhibits activation of Stat3[1]. |
| CAS | 183063-72-1 |
| Formula | C30H52N2O8 |
| Molar Mass | 568.74 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shailubhai K, et al. Atiprimod is an inhibitor of cancer cell proliferation and angiogenesis. J Exp Ther Oncol. 2004 Dec;4(4):267-79. |
Atiprimod dimaleate
CAS: 183063-72-1 F: C30H52N2O8 W: 568.74
Atiprimod (Azaspirane) (dimaleate) is an anti-proliferative and anti-angiogenic agent thatinhibits proliferation of all
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