| Bioactivity | Aspochalasin I exhibits cytotoxicity against cancer cells NCIH460, MCF-7 and SF-268, with IC50s of 22.1, 33.4 and 19.9 μM. Aspochalasin I inhibits melanogenesis (IC50 of 22.4 μM) through inhibition of tyrosinase, and can thus be used as whitening agent[1][2]. |
| CAS | 670225-69-1 |
| Formula | C24H35NO5 |
| Molar Mass | 417.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Choo SJ, et al., Aspochalasin I, a melanogenesis inhibitor from Aspergillus sp. J Microbiol Biotechnol. 2009 Apr;19(4):368-71 [2]. Zhou GX, et al., Aspochalasins I, J, and K: three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran Desert. J Nat Prod. 2004 Mar;67(3):328-32. |
Aspochalasin I
CAS: 670225-69-1 F: C24H35NO5 W: 417.54
Aspochalasin I exhibits cytotoxicity against cancer cells NCIH460, MCF-7 and SF-268, with IC50s of 22.1, 33.4 and 19.9
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