| Bioactivity | Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2]. | |||||||||
| Name | Aspartyl-alanyl-diketopiperazine | |||||||||
| CAS | 110954-19-3 | |||||||||
| Formula | C7H10N2O4 | |||||||||
| Molar Mass | 186.17 | |||||||||
| Appearance | Solid | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
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| Reference | [1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7. [2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41. |
Aspartyl-alanyl-diketopiperazine
CAS: 110954-19-3 F: C7H10N2O4 W: 186.17
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the
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