| Bioactivity | Artocarpesin is a flavonoid compound. Artocarpesin has inhibitory effects on methicillin-resistant Staphylococcus aureus (MRSA). Artocarpesin inhibits the production of NO, PGE2 and ROS by inhibiting COX-2 and iNOS expression, and plays an anti-inflammatory role. In addition, Artocarpesin inhibits platelet aggregation by inhibiting cyclic nucleotides and MAPKs, which can be used in the study of cardiovascular diseases[1][2][3]. |
| CAS | 3162-09-2 |
| Formula | C20H18O6 |
| Molar Mass | 354.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Manuel N G V, et al. Antimicrobial activity of artocarpesin from Artocarpus heterophyllus Lam. against methicillin-resistant Staphylococcus aureus (MRSA). Journal of Medicinal Plants Research, 2012, 6(34): 4879-82. [2]. Fang SC, et al. Anti-inflammatory effects of phenolic compounds isolated from the fruits of Artocarpus heterophyllus. J Agric Food Chem. 2008 Jun 25;56(12):4463-8. [3]. Kwon H W, et al. Artocarpesin acts on human platelet aggregation through inhibition of cyclic nucleotides and MAPKs. Applied Biological Chemistry, 2022, 65(1): 25. |