| Bioactivity | Aromatase-IN-4 (Compound 6a) is an aromatase (Aromatase) inhibitor. Aromatase-IN-4 exhibits anticancer activity, with GI50 values of 2.95 μM, 3.35 μM, 2.27 μM, 8.46 nM, and 1.56 μM against the MDAMB-231, MCF-7, A-549, NCI-H23, and A-498 cell lines, respectively[1]. Aromatase-IN-4 effectively blocks aromatase-dependent estrogen production[1]. |
| CAS | 3060588-16-8 |
| Formula | C23H18N6 |
| Molar Mass | 378.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sabale P, et al. Molecular Docking, Synthesis and Biological Evaluation of New Benzimidazole‐Pyridine Derivatives as Potential Aromatase Inhibitor for the Treatment of Cancer[J]. ChemistrySelect, 2024, 9(37): e202401797. |
Aromatase-IN-4
CAS: 3060588-16-8 F: C23H18N6 W: 378.43
Aromatase-IN-4 (Compound 6a) is an aromatase (Aromatase) inhibitor. Aromatase-IN-4 exhibits anticancer activity, with GI
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.