| Bioactivity | Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research[1]. |
| Name | Aromatase-IN-3 |
| Formula | C38H38N2O3 |
| Molar Mass | 570.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rani S, et al. Targeting aromatase to restrain oestrogen production and developing efficacious interventions against ER-positive cancer. Eur J Med Chem. 2023 Dec 31;265:116111. |