| Bioactivity | Argiotoxin 636 is a toxin and antagonist of the non-specific, non-competitive, and potent ionotropic glutamate receptor (iGluR). Argiotoxin 636 blocks excitatory synaptic transmission in neurons and has paralysis and muscle relaxation effects. Argiotoxin 636 can be used in the study of nervous system diseases[1][2]. |
| CAS | 105029-41-2 |
| Formula | C29H52N10O6 |
| Molar Mass | 636.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Adams ME, et al. Structures and biological activities of three synaptic antagonists from orb weaver spider venom. Biochem Biophys Res Commun. 1987 Oct 29;148(2):678-83. [2]. Ashe JH, et al. Argiotoxin-636 blocks excitatory synaptic transmission in rat hippocampal CA1 pyramidal neurons. Brain Res. 1989 Feb 20;480(1-2):234-41. |
Argiotoxin 636
CAS: 105029-41-2 F: C29H52N10O6 W: 636.79
Argiotoxin 636 is a toxin and antagonist of the non-specific, non-competitive, and potent ionotropic glutamate receptor
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