| Bioactivity | Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents[1]. |
| Invitro | Apoptosis inducer 9 (Compound A1) (5-10 μM, 12 hours) induces apoptosis in HepG-2 cells in a concentration-dependent manner[1].Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) triggers Cl-caspase-3, Cl-caspase-9 and Cl-PARP protein expression in HepG-2, thereby inducing apoptosis[1].Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) induces apoptosis by triggering the mitochondrial apoptosis pathway[1]. Cell Viability Assay[1] Cell Line: |
| Name | Apoptosis inducer 9 |
| CAS | 2551067-10-6 |
| Formula | C34H55N3O4S |
| Molar Mass | 601.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |