| Bioactivity | Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading lung cancer burden. Apoptosis inducer 8 significantly reduced the gal-1 protein level. Apoptosis inducer 8 is also a PET imaging agent[1]. |
| Invitro | Apoptosis inducer 8 (Compound 7c) exhibits an excellent growth inhibition against A-549, NCI-H460, MCF-7 and MDA-MB-23 cells with IC50 values of 0.63 ± 0.21, 0.99 ± 0.01, 1.3 ± 0.18 and 0.94 ± 0.02 µM, respectively[1]. |
| Name | Apoptosis inducer 8 |
| CAS | 2470024-51-0 |
| Formula | C29H22ClN5O2 |
| Molar Mass | 507.97 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sridhar Goud N, et al. Novel benzimidazole-triazole hybrids as apoptosis inducing agents in lung cancer: Design, synthesis, 18F-radiolabeling & galectin-1 inhibition studies. Bioorg Chem. 2020 Sep;102:104125. |
Apoptosis inducer 8
CAS: 2470024-51-0 F: C29H22ClN5O2 W: 507.97
Apoptosis inducer 8 (Compound 7c) is a galectin-1 (gal-1) mediated apoptosis-inducing agent against global major leading
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