| Bioactivity | Apoptosis inducer 24 (Compound 4) inhibits the proliferation of gastric cancer cells with IC50 of 1.2-4.8 μM. Apoptosis inducer 24 arrests cell cycle at G2/M phase, induces apoptosis in cell BGC-823, and causes mitochondrial dysfunction. Apoptosis inducer 24 exhibits antitumor efficacy in mice, without significant toxicity (LD50 is 91.2 mg/kg)[1]. |
| CAS | 2763063-09-6 |
| Formula | C55H70BNO9 |
| Molar Mass | 899.96 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li N, et al., New CDDO Arylboronate Ester Derivatives with High Selectivity and Low Toxicity. J Med Chem. 2024 Aug 22;67(16):14329-14344. |
Apoptosis inducer 24
CAS: 2763063-09-6 F: C55H70BNO9 W: 899.96
Apoptosis inducer 24 (Compound 4) inhibits the proliferation of gastric cancer cells with IC50 of 1.2-4.8 μM. Apoptosis
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.