| Bioactivity | Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19. |
| CAS | 870087-37-9 |
| Formula | C23H28Cl2N6O2 |
| Molar Mass | 491.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19 |
Apilimod hydrochloride
CAS: 870087-37-9 F: C23H28Cl2N6O2 W: 491.41
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and
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