| Bioactivity | Apicularen B is a V-ATPase inhibitor and cytotoxic macrolide that can be obtained from the myxobacterium Archangium gephyra. Apicularen B can be used in the study of V-ATPase-related diseases, such as osteopetrosis[1][2]. |
| Name | Apicularen B |
| CAS | 220757-06-2 |
| Formula | C33H44N2O11 |
| Molar Mass | 644.71 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Köteles I, et al. Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants. Molecules. 2020 Sep 2;25(17):4009. [2]. Hong J, et al. Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells. FEBS Lett. 2006 May 15;580(11):2723-30. |
Apicularen B
CAS: 220757-06-2 F: C33H44N2O11 W: 644.71
Apicularen B is a V-ATPase inhibitor and cytotoxic macrolide that can be obtained from the myxobacterium Archangium geph
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